The World Anti-Doping Agency (WADA) has launched an investigation after learning that newly-introduced sample bottles are susceptible to being opened manually.
New-generation BEREG-KIT Geneva security bottles made by Berlinger could potentially be opened if a sample is frozen, the organization said.
German journalist Hajo Seppelt said a documentary on ARD today would prove that "sample bottles for Winter Olympic Games are manipulable".
It comes with the fall-out from the Russian doping scheme at their home Sochi 2014 Winter Olympics and Paralympics still continuing.
A covert operation to replace tainted samples with clean ones was supposedly in operation at the Games.
Russia are being forced to compete neutrally at next month's Winter Olympics in Pyeongchang after being sanctioned due to the scandal, with numerous athletes stripped of medals and banned.
The news on the bottles is bound to cause concern with the Games in South Korea opening on February 9.
"The ARD doping editorial team was able to open sealed containers without trace," said Seppelt on Twitter.
WADA said they were alerted about the issue on January 19, with the new bottles only introduced in September last year in response to the Sochi scandal.
"WADA was informed by the WADA-accredited laboratory in Cologne, Germany, that security bottles of the new generation 'BEREG-KIT Geneva', introduced in September 2017 by Swiss manufacturer Berlinger Special AG (Berlinger), may potentially be susceptible to manual opening 'upon freezing' of a sample," the organization said.