The world's best swimmers will face up to seven anti-doping tests in the run up to August's Rio Olympics.
The International Swimming Federation (FINA) will oversee the initiative after critics said it had not done enough to fight doping.
The testing will mainly be done by leading national anti-doping agencies.
"FINA deserves a lot of credit for embracing the voice of clean athletes," said United States Anti-Doping Agency (USADA) boss Travis Tygart.
Figures within swimming suggested the idea for the sport's leading competitors to be tested between five and seven times ahead of the summer Games.
"Partnering with independent national anti-doing organizations to implement a strategic, global pre-Rio testing plan will help protect athletes' rights and the integrity of the sport of swimming," added Tygart.
Teaming up with USADA will be anti-doping agencies from most of the major swimming nations, including UK Anti-Doping.
FINA accepted the plan, which has not been formally agreed yet by every party, after a meeting with Tygart in Lausanne in January.
The promise to test every swimmer ranked in the top 10 times for all 34 Olympic events will represent a significant increase in the amount of testing the sport has been doing, although several stars will be ranked in more than one event.
But some leading coaches have already expressed their concerns to the BBC that the anti-doping agencies of Brazil, China and Russia are not involved.
Those three are currently among the most-tested nations by FINA itself and are all expected to win medals in Rio.
